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Single-mobile RNA-Seq reveals mobile heterogeneity of pluripotency changeover and X chromosome dynamics throughout early mouse advancement. X chromosome dosage influences DNA methylation dynamics in the course of reprogramming to mouse iPSCs. Erosion of X chromosome inactivation in human pluripotent cells initiates with XACT coating and depends on a distinct heterochromatin landscape. Single-mobile landscape of transcriptional heterogeneity and mobile fate choices during mouse early gastrulation.<br><br><br><br> The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells. Genome-scale CRISPR-Cas9 knockout screening in human cells. Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T. Activation of Akt signaling is enough to manage pluripotency in mouse and primate embryonic stem cells. Whole-genome bisulfite sequencing of two unique interconvertible DNA methylomes of mouse embryonic stem cells. 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