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The mesothelioma stage that is later are more difficult to treat.<br><br>In addition to the surgery and other mesothelioma treatment options doctors may recommend palliative treatment to manage symptoms such as pain or shortness of breath. They may also put an incision in your chest to remove fluid from your pleura or place you on a pump that drains your stomach.<br><br>Other treatment options are available in the event that mesothelioma has spread to other parts of the human body. This includes immunotherapy and targeted therapy. This is different from conventional chemotherapy, which employs medications to kill cancer cells and decrease their number. These treatments are based on the concept that mesothelioma cells have certain mutations that can be targeted by new drugs. 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